iPTMnet Report for Q6P158 (DHX57)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6P158 / DHX57_HUMAN
Protein Name Putative ATP-dependent RNA helicase DHX57
Gene Name Name: DHX57
Organism Homo sapiens (Human)

PRO ID PR:Q6P158
DAG View
PRO Name putative ATP-dependent RNA helicase DHX57 (human)
Definition A putative ATP-dependent RNA helicase DHX57 that is encoded in the genome of human.
Short Label hDHX57
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6P158 (DHX57) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
R51 Methylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S127 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
S132 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K256 Ubiquitination PhosphoSitePlus
T377 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S475 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S477 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S480 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
K512 Methylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
Y741 Phosphorylation PhosphoSitePlus
Y749 Phosphorylation PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
S1142 Phosphorylation PhosphoSitePlus
K1237 Ubiquitination PhosphoSitePlus
Y1261 Phosphorylation PhosphoSitePlus
S1267 Phosphorylation PhosphoSitePlus
Y1271 Phosphorylation PhosphoSitePlus
K1358 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation HPRD 18452278
S127 Phosphorylation HPRD 19413330, 17081983, 19007248, ...19691289, 19651622, 18669648, 20068231
S132 Phosphorylation HPRD 19413330, 18669648, 18452278
S475 Phosphorylation HPRD 18669648, 17081983, 18452278
S477 Phosphorylation HPRD 18669648, 17081983, 18452278
S480 Phosphorylation HPRD 18669648, 17081983, 18452278
Y749 Phosphorylation HPRD 20068231
S752 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 N31 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K512 T512 Biomuta DOID:3571 / liver cancer [ cosmic ]
S752 F752 Biomuta DOID:263 / kidney cancer [ cosmic ]