iPTMnet Report for Q6NZ67 (MZT2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6NZ67 / MZT2B_HUMAN
Protein Name Mitotic-spindle organizing protein 2B
Gene Name Name: MZT2B
Synonyms:FAM128B,MOZART2B;
Organism Homo sapiens (Human)

PRO ID PR:Q6NZ67
DAG View
PRO Name mitotic-spindle organizing protein 2B (human)
Definition A mitotic-spindle organizing protein 2B that is encoded in the genome of human.
Short Label hMZT2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6NZ67 (MZT2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
S34 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19690332, 20068231
T35 Phosphorylation PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
C80 Methylation IEDB 31844290
S96 Phosphorylation PhosphoSitePlus
T99 O-Glycosylation GlyGen 31373491
S100 O-Glycosylation GlyGen 31373491
T105 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
R133 Methylation PhosphoSitePlus
R136 Methylation PhosphoSitePlus
S139 Phosphorylation HPRD   PhosphoSitePlus 20068231
S152 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 20068231
T154 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S130 F130 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
S130 Y130 Biomuta DOID:4159 / skin cancer [ cosmic ]
R136 L136 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T154 A154 Biomuta DOID:9256 / colorectal cancer [ icgc ]