iPTMnet Report for Q6J4K2 (SLC8B1)
Protein Information
UniProt AC / UniProt ID | Q6J4K2 / NCLX_HUMAN |
Protein Name | Mitochondrial sodium/calcium exchanger protein precursor |
Gene Name | Name: SLC8B1 Synonyms:NCKX6; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6J4K2 |
PRO Name | mitochondrial sodium/calcium exchanger protein (human) |
Definition | A mitochondrial sodium/calcium exchanger protein that is encoded in the genome of human. |
Short Label | hSLC8B1 |
Category | organism-gene |
Q6J4K2 (SLC8B1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N60 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T70 | Phosphorylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y233 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
S258 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 26440884 | ||
S258 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 26440884 | |
K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
T456 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y240 | C240 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S258 | F258 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
T456 | S456 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |