Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6IA17 / SIGIR_HUMAN
Protein Name Single Ig IL-1-related receptor
Gene Name Name: SIGIRR
ORFNames:UNQ301/PRO342;
Organism Homo sapiens (Human)

PRO ID PR:Q6IA17
DAG View
PRO Name single Ig IL-1-related receptor (human)
Definition A single Ig IL-1-related receptor that is encoded in the genome of human.
Short Label hSIGIRR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6IA17 (SIGIRR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K179 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
Y395 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
Y402 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S364 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S388 L388 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S392 L392 Biomuta DOID:9256 / colorectal cancer [ cosmic ]