Protein Information

Cytoscape View


UniProt AC / UniProt ID Q63HM9 / PLCX3_HUMAN
Protein Name PI-PLC X domain-containing protein 3
Gene Name Name: PLCXD3
Organism Homo sapiens (Human)

PRO ID PR:Q63HM9
DAG View
PRO Name PI-PLC X domain-containing protein 3 (human)
Definition A PI-PLC X domain-containing protein 3 that is encoded in the genome of human.
Short Label hPLCXD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q63HM9 (PLCXD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 O-Glycosylation GlyGen 30620550
N83 N-Glycosylation GlyGen 29741879
T250 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
T267 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
N83 S83 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T250 N250 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
T250 I250 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T255 N255 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S262 R262 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
T267 P267 Biomuta DOID:1319 / brain cancer [ icgc ]