iPTMnet Report for Q5VXH4 (PRAMEF6)
Protein Information
UniProt AC / UniProt ID | Q5VXH4 / PRAM6_HUMAN |
Protein Name | PRAME family member 6 |
Gene Name | Name: PRAMEF6 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5VXH4 |
PRO Name | PRAME family member 6 (human) |
Definition | A PRAME family member 6 that is encoded in the genome of human. |
Short Label | hPRAMEF6 |
Category | organism-gene |
Q5VXH4 (PRAMEF6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
K183 | Methylation | score1 | PhosphoSitePlus | |||
S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
R246 | Methylation | score1 | PhosphoSitePlus | |||
T258 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K132 | I132 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K132 | N132 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K132 | T132 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
K132 | E132 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |