iPTMnet Report for Q5VWX1 (KHDRBS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VWX1 / KHDR2_HUMAN
Protein Name KH domain-containing, RNA-binding, signal transduction-associated protein 2
Gene Name Name: KHDRBS2
Synonyms:SLM1;
Organism Homo sapiens (Human)

PRO ID PR:Q5VWX1
DAG View
PRO Name KH domain-containing, RNA-binding, signal transduction-associated protein 2 (human)
Definition A KH domain-containing, RNA-binding, signal transduction-associated protein 2 that is encoded in the genome of human.
Short Label hKHDRBS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VWX1 (KHDRBS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
Y6 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S54 O-Glycosylation GlyGen 29485866, 30379171
K56 Acetylation PhosphoSitePlus
K69 Acetylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K79 Methylation PhosphoSitePlus
S87 Phosphorylation IEDB 35494241
T95 Phosphorylation HPRD 20068231
S106 Phosphorylation HPRD   PhosphoSitePlus 20068231
K112 Acetylation PhosphoSitePlus
R117 Methylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
R186 Methylation PhosphoSitePlus
R188 Methylation PhosphoSitePlus
R230 Methylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
R246 Methylation PhosphoSitePlus
R248 Methylation PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
R348 Methylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048101 (hKHDRBS2/PhosTyr+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 C20 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S25 P25 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K73 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K73 N73 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
S87 F87 Biomuta DOID:4159 / skin cancer [ cosmic ]
T95 K95 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S106 P106 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S106 T106 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S106 L106 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S106 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R117 W117 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S119 R119 Biomuta DOID:1324 / lung cancer [ cosmic ]
S119 N119 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y163 N163 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y163 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y163 C163 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R186 C186 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
R186 H186 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R230 S230 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R230 H230 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
R230 C230 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R240 K240 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
R246 Q246 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R246 * Biomuta DOID:184 / bone cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
R248 W248 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
R248 Q248 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y346 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R348 I348 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]