Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VWP2 / TET5C_HUMAN
Protein Name Terminal nucleotidyltransferase 5C
Gene Name Name: TENT5C
Synonyms:FAM46C;
Organism Homo sapiens (Human)

PRO ID PR:Q5VWP2
DAG View
PRO Name terminal nucleotidyltransferase 5C (human)
Definition A terminal nucleotidyltransferase 5C that is encoded in the genome of human.
Short Label hTENT5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VWP2 (TENT5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K49 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus   RLIMS-P 32807875
K126 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
T354 Phosphorylation RLIMS-P 32807875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K65 N65 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S74 F74 Biomuta DOID:1324 / lung cancer [ cosmic ]
K135 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K141 T141 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K234 N234 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K264 R264 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]