iPTMnet Report for Q5VW32 (BROX)
Protein Information
UniProt AC / UniProt ID | Q5VW32 / BROX_HUMAN |
Protein Name | BRO1 domain-containing protein BROX precursor |
Gene Name | Name: BROX Synonyms:BROFTI,C1orf58; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5VW32 |
PRO Name | BRO1 domain-containing protein BROX (human) |
Definition | A BRO1 domain-containing protein BROX that is encoded in the genome of human. |
Short Label | hBROX |
Category | organism-gene |
Q5VW32 (BROX) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Methylation | score1 | PhosphoSitePlus | |||
T136 | Phosphorylation | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K237 | Acetylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K283 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y331 | Phosphorylation | score1 | PhosphoSitePlus | |||
K334 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y348 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y20 | H20 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y20 | C20 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y281 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K295 | E295 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |