iPTMnet Report for Q5VUA4 (ZNF318)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VUA4 / ZN318_HUMAN
Protein Name Zinc finger protein 318
Gene Name Name: ZNF318
ORFNames:HRIHFB2436;
Organism Homo sapiens (Human)

PRO ID PR:Q5VUA4
DAG View
PRO Name zinc finger protein 318 (human)
Definition A zinc finger protein 318 that is encoded in the genome of human.
Short Label hZNF318
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VUA4 (ZNF318) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus   UniProt 23186163
S46 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus   UniProt 21406692
S81 Phosphorylation PhosphoSitePlus   UniProt 21406692
S89 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S141 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
T187 Phosphorylation PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus   UniProt 23186163
S214 Phosphorylation PhosphoSitePlus   UniProt 18669648, 19690332
S234 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
K281 Sumoylation PhosphoSitePlus
S284 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S294 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
Y451 Phosphorylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 20068231
S472 Phosphorylation PhosphoSitePlus   UniProt 23186163
K477 Ubiquitination PhosphoSitePlus
K483 Sumoylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus   UniProt 23186163
S512 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231
K536 Ubiquitination PhosphoSitePlus
K547 Sumoylation PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K578 Sumoylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
T686 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
R739 Methylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
R801 Methylation PhosphoSitePlus
T825 Phosphorylation PhosphoSitePlus
T829 Phosphorylation PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus
T842 Phosphorylation PhosphoSitePlus   UniProt 23186163
K845 Acetylation PhosphoSitePlus
R853 Methylation PhosphoSitePlus
S866 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
K921 Ubiquitination PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus
K1001 Acetylation PhosphoSitePlus
S1010 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1026 Phosphorylation PhosphoSitePlus
T1035 Phosphorylation PhosphoSitePlus
K1036 Ubiquitination PhosphoSitePlus
S1037 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S1043 Phosphorylation PhosphoSitePlus
S1046 Phosphorylation PhosphoSitePlus
T1048 Phosphorylation PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
T1091 Phosphorylation PhosphoSitePlus
Y1097 Phosphorylation PhosphoSitePlus
K1166 Ubiquitination PhosphoSitePlus
S1205 Phosphorylation PhosphoSitePlus
K1228 Acetylation PhosphoSitePlus
K1232 Acetylation PhosphoSitePlus
S1238 Phosphorylation PhosphoSitePlus
S1243 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S1267 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T1269 Phosphorylation PhosphoSitePlus
K1275 Acetylation PhosphoSitePlus
S1277 Phosphorylation PhosphoSitePlus
S1289 Phosphorylation PhosphoSitePlus
S1296 Phosphorylation PhosphoSitePlus
K1297 Ubiquitination PhosphoSitePlus
K1305 Acetylation PhosphoSitePlus
K1311 Acetylation PhosphoSitePlus
K1316 Acetylation PhosphoSitePlus
T1328 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
T1333 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...32938750, 34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
S1334 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
T1341 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...32938750, 34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
T1342 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...32938750, 34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
K1408 Ubiquitination PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S1533 Phosphorylation phospho.ELM 18669648, 15302935
S1558 Phosphorylation PhosphoSitePlus
Y1569 Phosphorylation PhosphoSitePlus
S1575 Phosphorylation PhosphoSitePlus
K1578 Acetylation PhosphoSitePlus
K1578 Ubiquitination PhosphoSitePlus
S1602 Phosphorylation PhosphoSitePlus
N1603 N-Glycosylation GlyGen 29671580
S1605 Phosphorylation PhosphoSitePlus
S1609 Phosphorylation PhosphoSitePlus
S1614 Phosphorylation PhosphoSitePlus
S1616 Phosphorylation PhosphoSitePlus
S1623 Phosphorylation PhosphoSitePlus
S1669 Phosphorylation PhosphoSitePlus
Y1671 Phosphorylation PhosphoSitePlus
R1679 Methylation PhosphoSitePlus
Y1686 Phosphorylation PhosphoSitePlus
T1688 Phosphorylation PhosphoSitePlus
T1693 O-Glycosylation GlyGen 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 32119511, 35289036, 35254053, 29237092
S1713 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1717 Phosphorylation PhosphoSitePlus
S1761 Phosphorylation PhosphoSitePlus
S1845 Phosphorylation PhosphoSitePlus
T1847 Phosphorylation PhosphoSitePlus
S1849 Phosphorylation PhosphoSitePlus
S1856 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1863 Phosphorylation PhosphoSitePlus
K1864 Methylation PhosphoSitePlus
K1866 Acetylation PhosphoSitePlus
K1866 Ubiquitination PhosphoSitePlus
S1869 Phosphorylation PhosphoSitePlus
T1883 Phosphorylation PhosphoSitePlus
K1886 Ubiquitination PhosphoSitePlus
S1888 Phosphorylation PhosphoSitePlus
S1896 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S1907 Phosphorylation PhosphoSitePlus
S1937 Phosphorylation PhosphoSitePlus
S1945 Phosphorylation IEDB   PhosphoSitePlus 27920218
Y1954 Phosphorylation PhosphoSitePlus
T1968 Phosphorylation PhosphoSitePlus
S1971 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2030 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2035 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2037 Phosphorylation PhosphoSitePlus
S2075 Phosphorylation IEDB   PhosphoSitePlus 27869121
T2085 Phosphorylation PhosphoSitePlus
S2091 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2101 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231, ...24275569
T2123 Phosphorylation PhosphoSitePlus
S2142 Phosphorylation PhosphoSitePlus
K2147 Ubiquitination PhosphoSitePlus
S2160 Phosphorylation PhosphoSitePlus
S2166 Phosphorylation PhosphoSitePlus
S2189 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S2192 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S2198 Phosphorylation PhosphoSitePlus
S2241 Phosphorylation PhosphoSitePlus
S2243 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation HPRD 19664995
S50 Phosphorylation HPRD 17081983
T52 Phosphorylation HPRD 17081983
S61 Phosphorylation HPRD 20068231
S79 Phosphorylation HPRD 19651622, 18669648, 20068231
S81 Phosphorylation HPRD 19651622, 18669648, 20068231
S109 Phosphorylation HPRD 20068231
S136 Phosphorylation HPRD 19413330, 17081983, 19664994, ...19691289, 18669648, 20068231
S173 Phosphorylation HPRD 17081983, 19691289, 18452278, ...19651622, 18669648, 20068231
Y205 Phosphorylation HPRD 18669648
S207 Phosphorylation HPRD 18077418
S214 Phosphorylation HPRD 18077418, 18669648
S305 Phosphorylation HPRD 17081983
S307 Phosphorylation HPRD 17081983
S464 Phosphorylation HPRD 19651622, 17081983, 20068231
S501 Phosphorylation HPRD 20068231
S527 Phosphorylation HPRD 19651622, 19691289, 20068231
S684 Phosphorylation HPRD 20068231
S692 Phosphorylation HPRD 20068231
S698 Phosphorylation HPRD 20068231
S709 Phosphorylation HPRD 19413330, 20068231
S1037 Phosphorylation HPRD 19651622, 19664995, 18452278
S1243 Phosphorylation HPRD 19651622, 17081983, 20068231
S1289 Phosphorylation HPRD 20068231
T1292 Phosphorylation HPRD 20068231
S1294 Phosphorylation HPRD 20068231
S1296 Phosphorylation HPRD 20068231
S1304 Phosphorylation HPRD 20068231
S1420 Phosphorylation HPRD 18669648, 20068231
N1603 N-Glycosylation PRO 29671580
T1615 Phosphorylation HPRD 18452278
S1616 Phosphorylation HPRD 18452278
S1623 Phosphorylation HPRD 17525332
S1713 Phosphorylation HPRD 18669648
T1847 Phosphorylation HPRD 19664995
S1856 Phosphorylation HPRD 20068231
T1883 Phosphorylation HPRD 18669648
S1896 Phosphorylation HPRD 18669648, 20068231
S1971 Phosphorylation HPRD 18452278
S2091 Phosphorylation HPRD 20068231
S2101 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19413330, 20068231
S2189 Phosphorylation HPRD 19413330, 18669648, 19664994
S2192 Phosphorylation HPRD 18669648
S2243 Phosphorylation HPRD 18669648, 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S59 L59 Biomuta DOID:4159 / skin cancer [ cosmic ]
S71 P71 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S160 C160 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S234 F234 Biomuta DOID:4159 / skin cancer [ cosmic ]
K281 E281 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S294 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S380 F380 Biomuta DOID:4159 / skin cancer [ cosmic ]
K444 N444 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K477 M477 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S512 R512 Biomuta DOID:3571 / liver cancer [ cosmic ]
K566 M566 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S653 L653 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
T829 S829 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R853 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S993 C993 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1010 G1010 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1166 T1166 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ]
S1289 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1292 I1292 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T1292 A1292 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1296 C1296 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1316 N1316 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1342 A1342 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1420 Y1420 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1575 N1575 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K1578 R1578 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y1671 C1671 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1713 C1713 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1864 N1864 Biomuta DOID:363 / uterine cancer [ icgc ]
S1896 F1896 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2075 F2075 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S2101 Y2101 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2160 Y2160 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S2189 F2189 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2243 F2243 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]