iPTMnet Report for Q5VTL8 (PRPF38B)
Protein Information
UniProt AC / UniProt ID | Q5VTL8 / PR38B_HUMAN |
Protein Name | Pre-mRNA-splicing factor 38B |
Gene Name | Name: PRPF38B |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5VTL8 |
PRO Name | pre-mRNA-splicing factor 38B (human) |
Definition | A pre-mRNA-splicing factor 38B that is encoded in the genome of human. |
Short Label | hPRPF38B |
Category | organism-gene |
Q5VTL8 (PRPF38B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330 | ||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K36 | Acetylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K101 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
K227 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
R253 | Methylation | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S266 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S268 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S272 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S289 | Phosphorylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983 | ||
S318 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983 | ||
S320 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983 | ||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
S385 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S448 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S471 | Phosphorylation | score1 | PhosphoSitePlus | |||
S473 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S475 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
T479 | Phosphorylation | score1 | PhosphoSitePlus | |||
S481 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
S493 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S503 | Phosphorylation | score1 | PhosphoSitePlus | |||
S527 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 16083285, 23186163, ... | ||
S529 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 16964243, ... | ||
S534 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17525332, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S5 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
S40 | Phosphorylation | score0 | HPRD | 20068231 | ||
T121 | Phosphorylation | score0 | HPRD | 19413330 | ||
T150 | Phosphorylation | score0 | HPRD | 20068231 | ||
T152 | Phosphorylation | score0 | HPRD | 20068231 | ||
S154 | Phosphorylation | score0 | HPRD | 20068231 | ||
S266 | Phosphorylation | score0 | HPRD | 20068231 | ||
S268 | Phosphorylation | score0 | HPRD | 20068231, 17924679 | ||
S288 | Phosphorylation | score0 | HPRD | 19651622 | ||
S289 | Phosphorylation | score0 | HPRD | 18452278 | ||
S290 | Phosphorylation | score0 | HPRD | 20068231, 18452278 | ||
S318 | Phosphorylation | score0 | HPRD | 20068231 | ||
S320 | Phosphorylation | score0 | HPRD | 20068231 | ||
S448 | Phosphorylation | score0 | HPRD | 20068231 | ||
S471 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S473 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S475 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S481 | Phosphorylation | score0 | HPRD | 19651622 | ||
S491 | Phosphorylation | score0 | HPRD | 20068231 | ||
S493 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S527 | Phosphorylation | score0 | HPRD | 16964243, 18767875, 15302935, ... | ||
S529 | Phosphorylation | score0 | HPRD | 16083285, 16964243, 18452278, ... | ||
S534 | Phosphorylation | score0 | HPRD | 19651622, 17525332, 18669648, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T150 | P150 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S154 | Y154 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y156 | H156 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K227 | T227 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S276 | * | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
S288 | F288 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S340 | N340 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S481 | R481 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S493 | I493 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |