Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T7W7 / TSTD2_HUMAN
Protein Name Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2
Gene Name Name: TSTD2
Synonyms:C9orf97;ORFNames:PP4189;
Organism Homo sapiens (Human)

PRO ID PR:Q5T7W7
DAG View
PRO Name thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (human)
Definition A thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 that is encoded in the genome of human.
Short Label hTSTD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T7W7 (TSTD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K26 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S269 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S274 Phosphorylation PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
C374 Methylation IEDB 31844290
K386 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
C419 Methylation IEDB 31844290
S464 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S269 Phosphorylation HPRD 18669648
S464 Phosphorylation HPRD 17924679
S468 Phosphorylation HPRD 17924679
S474 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K131 N131 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K239 E239 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y338 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K399 T399 Biomuta DOID:4159 / skin cancer [ cosmic ]
S464 N464 Biomuta DOID:4159 / skin cancer [ cosmic ]
S468 L468 Biomuta DOID:9256 / colorectal cancer [ cosmic ]