iPTMnet Report for Q5SY16 (NOL9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5SY16 / NOL9_HUMAN
Protein Name Polynucleotide 5'-hydroxyl-kinase NOL9
Gene Name Name: NOL9
Organism Homo sapiens (Human)

PRO ID PR:Q5SY16
DAG View
PRO Name polynucleotide 5'-hydroxyl-kinase NOL9 (human)
Definition A polynucleotide 5'-hydroxyl-kinase NOL9 that is encoded in the genome of human.
Short Label hNOL9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5SY16 (NOL9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
S4 Phosphorylation PhosphoSitePlus
K9 Methylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
C140 Methylation IEDB 31844290
K200 Methylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
C347 Methylation IEDB 31844290
K376 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y386 Phosphorylation PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
S395 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y397 Phosphorylation HPRD   PhosphoSitePlus 20068231
S427 Phosphorylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K485 Sumoylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
S487 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 20068231, ...18452278
T492 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K22 N22 Biomuta DOID:184 / bone cancer [ cosmic ]
S249 G249 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K440 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K459 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S487 G487 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]