iPTMnet Report for Q5SXM1 (ZNF678)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5SXM1 / ZN678_HUMAN
Protein Name Zinc finger protein 678
Gene Name Name: ZNF678
Organism Homo sapiens (Human)

PRO ID PR:Q5SXM1
DAG View
PRO Name zinc finger protein 678 (human)
Definition A zinc finger protein 678 that is encoded in the genome of human.
Short Label hZNF678
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5SXM1 (ZNF678) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K68 Ubiquitination PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K294 Sumoylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
T316 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K406 Sumoylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
T428 Phosphorylation PhosphoSitePlus
K462 Sumoylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K154 T154 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K173 R173 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T176 S176 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K294 T294 Biomuta DOID:363 / uterine cancer [ icgc ]
K319 N319 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K328 N328 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K406 N406 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S422 I422 Biomuta DOID:1612 / breast cancer [ cosmic ]