iPTMnet Report for Q5R372 (RABGAP1L)
Protein Information
UniProt AC / UniProt ID | Q5R372 / RBG1L_HUMAN |
Protein Name | Rab GTPase-activating protein 1-like |
Gene Name | Name: RABGAP1L Synonyms:HHL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5R372 |
PRO Name | Rab GTPase-activating protein 1-like isoforms 1/2/3/4/5/6/7/8/9 (human) |
Definition | A Rab GTPase-activating protein 1-like (human), isoforms 1, 2, 3, 4, 5, 6, 7, 8, and 9. |
Short Label | hRABGAP1L/iso:[1/2/3/4/5/6/7/8/9] |
Category | organism-seqgroup |
Q5R372 (RABGAP1L) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
S49 | Phosphorylation | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
C139 | Methylation | score1 | IEDB | 31844290 | ||
C214 | Methylation | score1 | IEDB | 31844290 | ||
S292 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y358 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y363 | Phosphorylation | score1 | PhosphoSitePlus | |||
T383 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y425 | Phosphorylation | score1 | PhosphoSitePlus | |||
T448 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y455 | Phosphorylation | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score1 | PhosphoSitePlus | |||
T471 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
T473 | Phosphorylation | score1 | PhosphoSitePlus | |||
S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
S480 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
S490 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
S495 | Phosphorylation | score1 | PhosphoSitePlus | |||
T498 | Phosphorylation | score1 | PhosphoSitePlus | |||
S502 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y511 | Phosphorylation | score1 | PhosphoSitePlus | |||
K536 | Ubiquitination | score1 | PhosphoSitePlus | |||
K570 | Ubiquitination | score1 | PhosphoSitePlus | |||
K593 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y604 | Phosphorylation | score1 | PhosphoSitePlus | |||
K605 | Ubiquitination | score1 | PhosphoSitePlus | |||
C641 | Methylation | score1 | IEDB | 31844290 | ||
C711 | Methylation | score1 | IEDB | 31844290 | ||
Y810 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S118 | Phosphorylation | score0 | HPRD | 20058876, 20068231 | ||
S119 | Phosphorylation | score0 | HPRD | 20068231 | ||
T471 | Phosphorylation | score0 | HPRD | 18669648 | ||
S480 | Phosphorylation | score0 | HPRD | 18669648 | ||
S490 | Phosphorylation | score0 | HPRD | 18669648 | ||
S495 | Phosphorylation | score0 | HPRD | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
T275 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C139 | F139 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S292 | C292 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y358 | C358 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T473 | S473 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T473 | N473 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S480 | L480 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S480 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S502 | F502 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K536 | N536 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
Y810 | C810 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |