iPTMnet Report for Q5PRF9 (SAMD4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5PRF9 / SMAG2_HUMAN
Protein Name Protein Smaug homolog 2
Gene Name Name: SAMD4B
Synonyms:SMAUG2;
Organism Homo sapiens (Human)

PRO ID PR:Q5PRF9
DAG View
PRO Name protein Smaug homolog 2 (human)
Definition A protein Smaug homolog 2 that is encoded in the genome of human.
Short Label hSAMD4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5PRF9 (SAMD4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S165 Phosphorylation PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S231 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S243 Phosphorylation HPRD   PhosphoSitePlus 20068231
S252 Phosphorylation HPRD   PhosphoSitePlus 20068231
T264 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S271 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18452278
S274 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S275 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S278 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K348 Methylation PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
T407 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16964243
T484 Phosphorylation RLIMS-P 21725060
Y499 Phosphorylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
T533 Phosphorylation PhosphoSitePlus
Y545 Phosphorylation PhosphoSitePlus
S555 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S557 Phosphorylation HPRD   PhosphoSitePlus   UniProt 15302935, 23186163, 20068231
S563 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
R570 Methylation PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
S592 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
R602 Methylation PhosphoSitePlus   UniProt 24129315
T606 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 20068231, 18220336
S607 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S609 Phosphorylation PhosphoSitePlus
R615 Methylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
S628 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
R634 Methylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus   RLIMS-P 21725060


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S231 R231 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S236 C236 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S236 F236 Biomuta DOID:4159 / skin cancer [ cosmic ]
T264 M264 Biomuta DOID:184 / bone cancer [ cosmic ]
S271 L271 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T405 P405 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T405 A405 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T484 A484 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T533 A533 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S557 L557 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S594 P594 Biomuta DOID:363 / uterine cancer [ icgc ]
S594 L594 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R634 C634 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R634 H634 Biomuta DOID:1319 / brain cancer [ icgc ]
S642 L642 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]