Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5JTV8 / TOIP1_HUMAN
Protein Name Torsin-1A-interacting protein 1
Gene Name Name: TOR1AIP1
Synonyms:LAP1;
Organism Homo sapiens (Human)

PRO ID PR:Q5JTV8
DAG View
PRO Name torsin-1A-interacting protein 1 (human)
Definition A torsin-1A-interacting protein 1 that is encoded in the genome of human.
Short Label hTOR1AIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5JTV8 (TOR1AIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T20 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S92 Phosphorylation IEDB 35494241
R115 Methylation PhosphoSitePlus
S135 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...25461922, 18847512, 18669648, 24275569, 20068231
S143 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T147 Phosphorylation PhosphoSitePlus
S154 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 17081983, ...18669648, 24275569, 19690332
S156 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 17081983, ...18669648, 24275569, 19690332
S157 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...24275569, 19690332
S163 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S164 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648, 17081983
T166 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S169 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T171 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S186 O-Glycosylation GlyGen 33214551, 28510447, 22661428, ...30059200, 35254053, 34019948, 33465208, 29351928, 31373491
S186 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y200 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S215 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569, ...25461922
T220 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 25461922, ...18669648, 24275569, 19690332, 20068231
S227 Phosphorylation PhosphoSitePlus   UniProt 19690332
S228 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
T233 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S266 O-Glycosylation GlyGen 33214551, 28510447, 22661428, ...30059200, 35254053, 34019948, 33465208, 29351928, 31373491
S266 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
N268 N-Glycosylation GlyGen 24190977
T270 O-Glycosylation GlyGen 33214551, 28510447, 22661428, ...30059200, 35254053, 34019948, 33465208, 29351928, 31373491
K274 Ubiquitination PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
R300 Methylation PhosphoSitePlus
S305 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 25461922
K308 Ubiquitination PhosphoSitePlus
S309 O-Glycosylation GlyGen 33214551, 28510447, 22661428, ...30059200, 35254053, 34019948, 33465208, 29351928, 31373491
S309 Phosphorylation PhosphoSitePlus   UniProt 25461922
S315 O-Glycosylation GlyGen 33465208
S315 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S317 O-Glycosylation GlyGen 33465208
S317 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T318 O-Glycosylation GlyGen 33465208
S319 O-Glycosylation GlyGen 33465208
S320 Phosphorylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
N399 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S400 O-Glycosylation GlyGen 34846842, 33214551, 28510447, ...22661428, 30059200, 35254053, 34019948, 33465208, 29351928, 31373491
S405 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S50 Phosphorylation HPRD 20068230
S60 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 18669648
S143 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20058876, 20068231
T147 Phosphorylation HPRD 20068231
S154 Phosphorylation HPRD 18691976, 17525332, 18452278, ...19651622, 18669648, 20166139, 20068231
S156 Phosphorylation HPRD 18691976, 17525332, 18452278, ...19651622, 18669648, 20166139, 19415658, 20068231
S157 Phosphorylation HPRD 18452278, 19651622, 18669648, ...20166139, 19415658, 20068231
S163 Phosphorylation HPRD 18669648
S164 Phosphorylation HPRD 20166139, 17525332, 18669648, ...18452278
T166 Phosphorylation HPRD 20166139, 18669648, 20068231
S169 Phosphorylation HPRD 17525332
S186 Phosphorylation HPRD 18669648
S215 Phosphorylation HPRD 19413330, 18669648, 19415658, ...20068231
T220 Phosphorylation HPRD 19413330, 19664994, 18452278, ...18669648, 19415658, 20068231
S228 Phosphorylation HPRD 18452278
S231 Phosphorylation HPRD 18452278
S242 Phosphorylation HPRD 19651622
S245 Phosphorylation HPRD 19651622
S254 Phosphorylation HPRD 18077418
S305 Phosphorylation HPRD 18669648
S315 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S317 Phosphorylation HPRD 18669648
T318 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S179 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S92 P92 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S143 F143 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T166 S166 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T171 M171 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S179 I179 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T220 I220 Biomuta DOID:363 / uterine cancer [ icgc ]
S230 I230 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K236 T236 Biomuta DOID:263 / kidney cancer [ cosmic ]
S245 Y245 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S252 L252 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K274 N274 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T294 A294 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S319 P319 Biomuta DOID:4159 / skin cancer [ cosmic ]
K334 E334 Biomuta DOID:1324 / lung cancer [ cosmic ]
S400 N400 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K539 E539 Biomuta DOID:3571 / liver cancer [ cosmic ]