iPTMnet Report for Q5JPI9 (EEF1AKMT2)
Protein Information
UniProt AC / UniProt ID | Q5JPI9 / EFMT2_HUMAN |
Protein Name | EEF1A lysine methyltransferase 2 |
Gene Name | Name: EEF1AKMT2 Synonyms:C10orf138,METTL10; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5JPI9 |
PRO Name | EEF1A lysine methyltransferase 2 (human) |
Definition | An EEF1A lysine methyltransferase 2 that is encoded in the genome of human. |
Short Label | hEEF1AKMT2 |
Category | organism-gene |
Q5JPI9 (EEF1AKMT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S17 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648 | ||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648, 23186163 | ||
Y52 | Phosphorylation | score1 | PhosphoSitePlus | |||
T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
C257 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T55 | A55 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K169 | N169 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
Y173 | C173 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
C257 | F257 | Biomuta | DOID:1324 / lung cancer [ icgc ] |