iPTMnet Report for Q5FBB7 (SGO1)
Protein Information
UniProt AC / UniProt ID | Q5FBB7 / SGO1_HUMAN |
Protein Name | Shugoshin 1 |
Gene Name | Name: SGO1 Synonyms:SGOL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5FBB7 |
PRO Name | shugoshin 1 (human) |
Definition | A shugoshin 1 that is encoded in the genome of human. |
Short Label | hSGO1 |
Category | organism-gene |
Q5FBB7 (SGO1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | P51955 (NEK2) | score3 | neXtProt PhosphoSitePlus Signor UniProt | 17621308 | |
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
K23 | Acetylation | score1 | PhosphoSitePlus | |||
K25 | Acetylation | score1 | PhosphoSitePlus | |||
S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | P53350 (PLK1) | score2 | neXtProt | 18331714 | |
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
T146 | Phosphorylation | P53350 (PLK1) | score2 | neXtProt | 18331714 | |
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
T346 | Phosphorylation | P06493 (CDK1) | score4 | IntAct PhosphoSitePlus RLIMS-P Signor | 24055156, 23242214, 29263825, ... | |
T417 | Phosphorylation | score1 | PhosphoSitePlus | |||
T425 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T429 | Phosphorylation | score1 | PhosphoSitePlus | |||
T433 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S436 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 23186163, 19015261, 18220336 | ||
S440 | Phosphorylation | score0 | RLIMS-P | 19015261 | ||
Y450 | Phosphorylation | score1 | PhosphoSitePlus | |||
K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
S507 | Phosphorylation | P51955 (NEK2) | score4 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 18669648, 17621308, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S256 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 20068231 | ||
T425 | Phosphorylation | score0 | HPRD | 18669648 | ||
T429 | Phosphorylation | score0 | HPRD | 20068231 | ||
T433 | Phosphorylation | score0 | HPRD | 18669648 | ||
S436 | Phosphorylation | score0 | HPRD | 20068231 | ||
S459 | Phosphorylation | score0 | HPRD | 20068231 | ||
S461 | Phosphorylation | score0 | HPRD | 20068231 | ||
S468 | Phosphorylation | score0 | HPRD | 19007248 | ||
T500 | Phosphorylation | score0 | HPRD | 20068231 | ||
S507 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S207 | Phosphorylation | score0 | HPRD | 20068231 | ||
S209 | Phosphorylation | score0 | HPRD | 20068231 | ||
S216 | Phosphorylation | score0 | HPRD | 19007248 | ||
T248 | Phosphorylation | score0 | HPRD | 20068231 | ||
S255 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S190 | Phosphorylation | score0 | HPRD | 20068231 | ||
S192 | Phosphorylation | score0 | HPRD | 20068231 | ||
S199 | Phosphorylation | score0 | HPRD | 19007248 | ||
T231 | Phosphorylation | score0 | HPRD | 20068231 | ||
S238 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S207 | Phosphorylation | score0 | HPRD | 20068231 | ||
S209 | Phosphorylation | score0 | HPRD | 20068231 | ||
S216 | Phosphorylation | score0 | HPRD | 19007248 | ||
T248 | Phosphorylation | score0 | HPRD | 20068231 | ||
S255 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S190 | Phosphorylation | score0 | HPRD | 20068231 | ||
S192 | Phosphorylation | score0 | HPRD | 20068231 | ||
S199 | Phosphorylation | score0 | HPRD | 19007248 | ||
T231 | Phosphorylation | score0 | HPRD | 20068231 | ||
S238 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S256 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 20068231 | ||
T425 | Phosphorylation | score0 | HPRD | 18669648 | ||
T429 | Phosphorylation | score0 | HPRD | 20068231 | ||
T433 | Phosphorylation | score0 | HPRD | 18669648 | ||
S436 | Phosphorylation | score0 | HPRD | 20068231 | ||
S459 | Phosphorylation | score0 | HPRD | 20068231 | ||
S461 | Phosphorylation | score0 | HPRD | 20068231 | ||
S468 | Phosphorylation | score0 | HPRD | 19007248 | ||
T500 | Phosphorylation | score0 | HPRD | 20068231 | ||
S507 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:P53350 (hPLK1) | Interaction | PR:Q5FBB7 (hSGO1) | PRO | ||
PR:Q53HL2 (hCDCA8) | Interaction | PR:Q5FBB7 (hSGO1) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:Q96GD4 (hAURKB) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:O60566 (hBUB1B) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:P53350 (hPLK1) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:P30153 (hPPP2R1A) | PRO | 16580887 | |
PR:Q5FBB7 (hSGO1) | Interaction | PR:P67775 (hPPP2CA) | PRO | 16580887 | |
PR:Q5FBB7 (hSGO1) | Interaction | PR:Q53HL2 (hCDCA8) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:Q9NQS7 (hINCENP) | PRO | ||
PR:Q5FBB7 (hSGO1) | Interaction | PR:Q13362 (hPPP2R5C) | PRO | 16580887 | |
PR:Q9NQS7 (hINCENP) | Interaction | PR:Q5FBB7 (hSGO1) | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S14 | R14 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S38 | C38 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
S119 | F119 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S201 | N201 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S238 | Y238 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] | |
S255 | Y255 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y450 | C450 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K454 | T454 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S507 | Y507 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |