iPTMnet Report for Q56P03 (EAPP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q56P03 / EAPP_HUMAN
Protein Name E2F-associated phosphoprotein
Gene Name Name: EAPP
Synonyms:C14orf11;ORFNames:BM-036;
Organism Homo sapiens (Human)

PRO ID PR:Q56P03
DAG View
PRO Name E2F-associated phosphoprotein (human)
Definition An E2F-associated phosphoprotein that is encoded in the genome of human.
Short Label hEAPP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q56P03 (EAPP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 20068231
S17 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S24 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
S25 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
S26 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
T37 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 24275569
T50 Phosphorylation HPRD   PhosphoSitePlus 17081983
S53 Phosphorylation HPRD   PhosphoSitePlus 17081983
S55 Phosphorylation HPRD   PhosphoSitePlus 17081983
S56 Phosphorylation HPRD   PhosphoSitePlus 17081983
S57 Phosphorylation HPRD   PhosphoSitePlus 17081983
K79 Sumoylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S82 Phosphorylation HPRD   PhosphoSitePlus 19413330
T85 Phosphorylation HPRD   PhosphoSitePlus 19413330
S87 Phosphorylation HPRD   PhosphoSitePlus 20068231
S88 Phosphorylation HPRD 20068231
S89 Phosphorylation PhosphoSitePlus
K93 Sumoylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation HPRD   PhosphoSitePlus 20068231
S109 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 24275569, 19690332, 20068231
S111 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18669648, 24275569, 19690332, 20068231
T121 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K130 Sumoylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K79 R79 Biomuta DOID:3571 / liver cancer [ cosmic ]
S82 Y82 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S111 F111 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T121 I121 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y220 C220 Biomuta DOID:3571 / liver cancer [ cosmic ]