iPTMnet Report for Q53TN4 (CYBRD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53TN4 / CYBR1_HUMAN
Protein Name Plasma membrane ascorbate-dependent reductase CYBRD1
Gene Name Name: CYBRD1
Synonyms:DCYTB;
Organism Homo sapiens (Human)

PRO ID PR:Q53TN4
DAG View
PRO Name plasma membrane ascorbate-dependent reductase CYBRD1 (human)
Definition A plasma membrane ascorbate-dependent reductase CYBRD1 that is encoded in the genome of human.
Short Label hCYBRD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53TN4 (CYBRD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S185 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus   UniProt 23186163
T233 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S248 Phosphorylation HPRD 18578522
S253 Phosphorylation HPRD 18578522
S260 Phosphorylation HPRD 18578522, 18669648, 17081983
S262 Phosphorylation HPRD 18669648
T285 Phosphorylation HPRD 18578522, 19415658, 18669648, ...20068231, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S185 P185 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S232 F232 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S248 Y248 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S260 L260 Biomuta DOID:4159 / skin cancer [ cosmic ]
S266 I266 Biomuta DOID:3571 / liver cancer [ cosmic ]
S266 N266 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]