iPTMnet Report for Q53T59 (HS1BP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q53T59 / H1BP3_HUMAN
Protein Name HCLS1-binding protein 3
Gene Name Name: HS1BP3
Organism Homo sapiens (Human)

PRO ID PR:Q53T59
DAG View
PRO Name HCLS1-binding protein 3 (human)
Definition An HCLS1-binding protein 3 that is encoded in the genome of human.
Short Label hHS1BP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q53T59 (HS1BP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 20068231
S3 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T9 Phosphorylation HPRD 20068231
T18 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
T137 Phosphorylation HPRD 20068231
S139 Phosphorylation HPRD   PhosphoSitePlus   UniProt 24275569, 23186163, 16964243, ...20068231
T146 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S194 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 18452278, ...18669648, 18707149, 20068231
T229 Phosphorylation PhosphoSitePlus
S249 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 24275569, 18707149
S254 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
K337 Acetylation PhosphoSitePlus   UniProt 19608861


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T137 A137 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S139 F139 Biomuta DOID:363 / uterine cancer [ icgc ]
S139 T139 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T146 S146 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S194 F194 Biomuta DOID:4159 / skin cancer [ cosmic ]
S249 F249 Biomuta DOID:10534 / stomach cancer [ cosmic ]