iPTMnet Report for Q53R41 (FASTKD1)
Protein Information
UniProt AC / UniProt ID | Q53R41 / FAKD1_HUMAN |
Protein Name | FAST kinase domain-containing protein 1, mitochondrial precursor |
Gene Name | Name: FASTKD1 Synonyms:KIAA1800; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q53R41 |
PRO Name | FAST kinase domain-containing protein 1, mitochondrial (human) |
Definition | A FAST kinase domain-containing protein 1, mitochondrial that is encoded in the genome of human. |
Short Label | hFASTKD1 |
Category | organism-gene |
Q53R41 (FASTKD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
T83 | Phosphorylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y122 | Phosphorylation | score1 | PhosphoSitePlus | |||
T124 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y168 | Phosphorylation | score1 | PhosphoSitePlus | |||
S170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S305 | Phosphorylation | score1 | PhosphoSitePlus | |||
K360 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K374 | Ubiquitination | score1 | PhosphoSitePlus | |||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y406 | Phosphorylation | score1 | PhosphoSitePlus | |||
K478 | Ubiquitination | score1 | PhosphoSitePlus | |||
K482 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y486 | Phosphorylation | score1 | PhosphoSitePlus | |||
S496 | Phosphorylation | score1 | PhosphoSitePlus | |||
T546 | Phosphorylation | score1 | PhosphoSitePlus | |||
T551 | Phosphorylation | score1 | PhosphoSitePlus | |||
S619 | Phosphorylation | score1 | IEDB | 32387766 | ||
K691 | Ubiquitination | score1 | PhosphoSitePlus | |||
C716 | Methylation | score1 | IEDB | 31844290 | ||
Y726 | Phosphorylation | score1 | PhosphoSitePlus | |||
K728 | Ubiquitination | score1 | PhosphoSitePlus | |||
K737 | Ubiquitination | score1 | PhosphoSitePlus | |||
K785 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y810 | Phosphorylation | score1 | PhosphoSitePlus | |||
K844 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K374 | T374 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y486 | C486 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S619 | F619 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S619 | C619 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
K728 | I728 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
K728 | N728 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |