iPTMnet Report for Q53H96 (PYCR3)
Protein Information
| UniProt AC / UniProt ID | Q53H96 / P5CR3_HUMAN |
| Protein Name | Pyrroline-5-carboxylate reductase 3 |
| Gene Name | Name: PYCR3 Synonyms:PYCRL; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q53H96 |
| PRO Name | pyrroline-5-carboxylate reductase 3 (human) |
| Definition | A pyrroline-5-carboxylate reductase 3 that is encoded in the genome of human. |
| Short Label | hPYCR3 |
| Category | organism-gene |
DAG ViewQ53H96 (PYCR3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T236 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S147 | I147 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| S147 | G147 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T216 | M216 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T216 | A216 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |
