iPTMnet Report for Q53GT1 (KLHL22)
Protein Information
UniProt AC / UniProt ID | Q53GT1 / KLH22_HUMAN |
Protein Name | Kelch-like protein 22 |
Gene Name | Name: KLHL22 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q53GT1 |
PRO Name | kelch-like protein 22 (human) |
Definition | A kelch-like protein 22 that is encoded in the genome of human. |
Short Label | hKLHL22 |
Category | organism-gene |
Q53GT1 (KLHL22) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22223895 | ||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
S281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
C465 | Methylation | score1 | IEDB | 31844290 | ||
K494 | Acetylation | score1 | PhosphoSitePlus | |||
C516 | Methylation | score1 | IEDB | 31844290 | ||
Y517 | Phosphorylation | score1 | PhosphoSitePlus | |||
T605 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S18 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S18 | L18 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |