iPTMnet Report for Q53G59 (KLHL12)
Protein Information
UniProt AC / UniProt ID | Q53G59 / KLH12_HUMAN |
Protein Name | Kelch-like protein 12 |
Gene Name | Name: KLHL12 Synonyms:C3IP1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q53G59 |
PRO Name | kelch-like protein 12 (human) |
Definition | A kelch-like protein 12 that is encoded in the genome of human. |
Short Label | hKLHL12 |
Category | organism-gene |
Q53G59 (KLHL12) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T31 | Phosphorylation | score1 | PhosphoSitePlus | |||
C33 | Methylation | score1 | IEDB | 31844290 | ||
T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
C111 | Methylation | score1 | IEDB | 31844290 | ||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y231 | Phosphorylation | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
K462 | Ubiquitination | score1 | PhosphoSitePlus | |||
C511 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C111 | Y111 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
C111 | S111 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K181 | T181 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K301 | N301 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
C511 | W511 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |