iPTMnet Report for Q4VXU2 (PABPC1L)
Protein Information
| UniProt AC / UniProt ID | Q4VXU2 / PAP1L_HUMAN |
| Protein Name | Polyadenylate-binding protein 1-like |
| Gene Name | Name: PABPC1L Synonyms:C20orf119; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q4VXU2 |
| PRO Name | polyadenylate-binding protein 1-like (human) |
| Definition | A polyadenylate-binding protein 1-like that is encoded in the genome of human. |
| Short Label | hPABPC1L |
| Category | organism-gene |
Q4VXU2 (PABPC1L) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R166 | Methylation | score1 | PhosphoSitePlus | |||
| K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y291 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K333 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C339 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K348 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y364 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S32 | Y32 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S96 | P96 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| R166 | H166 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| R166 | C166 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y291 | H291 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| C339 | F339 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S341 | F341 | Biomuta | [ cosmic ] | |
| S342 | F342 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View