iPTMnet Report for Q4G163 (FBXO43)
Protein Information
UniProt AC / UniProt ID | Q4G163 / FBX43_HUMAN |
Protein Name | F-box only protein 43 |
Gene Name | Name: FBXO43 Synonyms:EMI2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q4G163 |
PRO Name | F-box only protein 43 (human) |
Definition | An F-box only protein 43 that is encoded in the genome of human. |
Short Label | hFBXO43 |
Category | organism-gene |
Q4G163 (FBXO43) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 15753281 | ||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
T138 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
T234 | Phosphorylation | Q9UQM7 (CAMK2A) | score3 | PhosphoSitePlus UniProt | 16407128 | |
S334 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 15753281 | ||
S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y503 | Phosphorylation | score1 | PhosphoSitePlus | |||
K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
T551 | Phosphorylation | score1 | PhosphoSitePlus | |||
T607 | Phosphorylation | score1 | PhosphoSitePlus | |||
S618 | Phosphorylation | score1 | PhosphoSitePlus | |||
S619 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T18 | S18 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S53 | F53 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S121 | F121 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] | |
T138 | A138 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
S198 | F198 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T234 | K234 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |