iPTMnet Report for Q495A1 (TIGIT)
Protein Information
UniProt AC / UniProt ID | Q495A1 / TIGIT_HUMAN |
Protein Name | T-cell immunoreceptor with Ig and ITIM domains precursor |
Gene Name | Name: TIGIT Synonyms:VSIG9,VSTM3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q495A1 |
PRO Name | T-cell immunoreceptor with Ig and ITIM domains (human) |
Definition | A T cell immunoreceptor with Ig and ITIM domains that is encoded in the genome of human. |
Short Label | hTIGIT |
Category | organism-gene |
Q495A1 (TIGIT) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
T155 | Phosphorylation | score1 | PhosphoSitePlus | |||
T164 | Phosphorylation | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y225 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23154388 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T164 | P164 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |