iPTMnet Report for Q3U182 (Crtc2)
Protein Information
UniProt AC / UniProt ID | Q3U182 / CRTC2_MOUSE |
Protein Name | CREB-regulated transcription coactivator 2 |
Gene Name | Name: Crtc2 Synonyms:Torc2; |
Organism | Mus musculus (Mouse) |
PRO ID | PR:Q3U182 |
PRO Name | CREB-regulated transcription coactivator 2 (mouse) |
Definition | A CREB-regulated transcription coactivator 2 that is encoded in the genome of mouse. |
Short Label | mCRTC2 |
Category | organism-gene |
Q3U182 (Crtc2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S15 | Phosphorylation | score0 | RLIMS-P | 30337688 | ||
T37 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
R51 | Methylation | score2 | UniProt | 24570487 | ||
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S70 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
S70 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 21183079, 28235073 | ||
S86 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
R99 | Methylation | score2 | UniProt | 24570487 | ||
R120 | Methylation | score2 | UniProt | 24570487 | ||
Y121 | Phosphorylation | score1 | PhosphoSitePlus | |||
R123 | Methylation | score2 | UniProt | 24570487 | ||
S127 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S128 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
Y130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 33434948, 30232001 | ||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
R161 | Methylation | score4 | PhosphoSitePlus UniProt | 24129315, 24570487 | ||
S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
R168 | Methylation | score2 | UniProt | 24570487 | ||
T169 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 28235073 | ||
S171 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
S171 | Phosphorylation | Q8CFH6 (Sik2) | score4 | PRO PhosphoSitePlus RLIMS-P UniProt | 29211348, 20551288, 16684769, ... | |
S173 | O-Glycosylation | score3 | GlyGen PhosphoSitePlus | 18323454 | ||
S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
T187 | Phosphorylation | score1 | PhosphoSitePlus | |||
K229 | Acetylation | score1 | PhosphoSitePlus | |||
S275 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 20551288, 30611118 | ||
S307 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 20551288 | ||
T308 | Phosphorylation | score0 | RLIMS-P | 27239959 | ||
T309 | Phosphorylation | score0 | RLIMS-P | 28589878 | ||
S358 | Phosphorylation | score0 | RLIMS-P | 17805301 | ||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21183079 | ||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
S457 | Phosphorylation | score1 | PhosphoSitePlus | |||
T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
T463 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y489 | Phosphorylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
S493 | Phosphorylation | score1 | PhosphoSitePlus | |||
T502 | Phosphorylation | score1 | PhosphoSitePlus | |||
S612 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 17242355, 21183079 | ||
S622 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21183079 | ||
S623 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21183079 | ||
S627 | Phosphorylation | score1 | PhosphoSitePlus | |||
K628 | Acetylation | score1 | PhosphoSitePlus | |||
K628 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000045523 (mCRTC2/Phos:1) | pS171 | PRO | 16684769 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P31749 (AKT1) | T450 | Q3U182 (Crtc2) | inhibited_association | eFIP | 30428057 | |
Phosphorylation | P42345 (MTOR) | S2481 | Q3U182 (Crtc2) | unknown | eFIP | 24479521 | |
Phosphorylation | Q6R327 (RICTOR) | T1135 | Q3U182 (Crtc2) | unknown | eFIP | 32642408 | |
Phosphorylation | Q9BPZ7 (MAPKAP1) | T398 | Q3U182 (Crtc2) | unknown | eFIP | 31798957 | |
Phosphorylation | Q9BPZ7 (MAPKAP1) | T398 | Q3U182 (Crtc2) | unknown | eFIP | 24481632 |