iPTMnet Report for Q3KR37 (GRAMD1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q3KR37 / ASTRB_HUMAN
Protein Name Protein Aster-B
Gene Name Name: GRAMD1B
Synonyms:KIAA1201;ORFNames:UNQ3032/PRO9834;
Organism Homo sapiens (Human)

PRO ID PR:Q3KR37
DAG View
PRO Name protein Aster-B (human)
Definition A protein Aster-B that is encoded in the genome of human.
Short Label hGRAMD1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q3KR37 (GRAMD1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S30 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T32 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
R121 Methylation PhosphoSitePlus
T269 Phosphorylation phospho.ELM 18669648
S274 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y389 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T394 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T444 Phosphorylation PhosphoSitePlus
Y484 Phosphorylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
Y527 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus   UniProt 23186163
S556 Phosphorylation PhosphoSitePlus
S581 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T584 Phosphorylation PhosphoSitePlus
T585 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T587 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K695 Ubiquitination PhosphoSitePlus
Y726 Phosphorylation PhosphoSitePlus
T727 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation HPRD 18669648
T269 Phosphorylation HPRD 18669648
S274 Phosphorylation HPRD 19651622, 18669648
Y389 Phosphorylation HPRD 18669648
T394 Phosphorylation HPRD 18669648
S550 Phosphorylation HPRD 19651622
S581 Phosphorylation HPRD 18669648, 20068231
T585 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S69 Y69 Biomuta DOID:3565 / meningioma [ cosmic ]
S80 R80 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S88 N88 Biomuta [ cosmic ]
R121 G121 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S274 C274 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y504 H504 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S533 I533 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S581 N581 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T585 M585 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T727 R727 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]