Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2VWP7 / PRTG_HUMAN
Protein Name Protogenin precursor
Gene Name Name: PRTG
Organism Homo sapiens (Human)

PRO ID PR:Q2VWP7
DAG View
PRO Name protogenin (human)
Definition A protogenin that is encoded in the genome of human.
Short Label hPRTG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2VWP7 (PRTG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T178 Phosphorylation PhosphoSitePlus
S196 O-Glycosylation GlyGen 29351928
Y302 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus
N630 N-Glycosylation GlyGen 24190977
Y729 Phosphorylation PhosphoSitePlus
N754 N-Glycosylation GlyGen 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S196 R196 Biomuta DOID:3571 / liver cancer [ cosmic ]
S369 L369 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
T610 M610 Biomuta [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1115 / sarcoma [ icgc ]