iPTMnet Report for Q2PPJ7 (RALGAPA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2PPJ7 / RGPA2_HUMAN
Protein Name Ral GTPase-activating protein subunit alpha-2
Gene Name Name: RALGAPA2
Synonyms:C20orf74,KIAA1272;
Organism Homo sapiens (Human)

PRO ID PR:Q2PPJ7
DAG View
PRO Name Ral GTPase-activating protein subunit alpha-2 (human)
Definition A Ral GTPase-activating protein subunit alpha-2 that is encoded in the genome of human.
Short Label hRALGAPA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2PPJ7 (RALGAPA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation IEDB 35494241
Y316 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S486 Phosphorylation PRO   PhosphoSitePlus   UniProt 16490346, 23186163, 24275569
T488 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
K675 Ubiquitination PhosphoSitePlus
K679 Methylation PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PRO   PhosphoSitePlus   UniProt 16490346, 23186163
S701 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PRO   PhosphoSitePlus   UniProt 16490346
T716 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
T767 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
C775 S-Nitrosylation dbSNO 26338901
T813 Phosphorylation PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
S820 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...24275569
S821 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S844 Phosphorylation PhosphoSitePlus
S846 Phosphorylation PhosphoSitePlus
T847 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S1493 Phosphorylation PhosphoSitePlus
K1508 Ubiquitination PhosphoSitePlus
S1593 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1839 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S694 Phosphorylation HPRD 20058876
S820 Phosphorylation HPRD 20166139, 18669648
S821 Phosphorylation HPRD 18669648


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049005 (hRALGAPA2/Phos:1) pS486,pS696,pT715 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S373 I373 Biomuta DOID:363 / uterine cancer [ icgc ]
K425 E425 Biomuta DOID:4159 / skin cancer [ cosmic ]
S465 I465 Biomuta DOID:1324 / lung cancer [ cosmic ]
S465 R465 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ]
T488 I488 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S492 N492 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K674 N674 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K679 Q679 Biomuta DOID:1324 / lung cancer [ cosmic ]
T716 M716 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S764 R764 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S844 G844 Biomuta DOID:363 / uterine cancer [ icgc ]
S844 N844 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S846 R846 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]