iPTMnet Report for Q2M3C7 (SPHKAP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2M3C7 / SPKAP_HUMAN
Protein Name A-kinase anchor protein SPHKAP
Gene Name Name: SPHKAP
Synonyms:KIAA1678,SKIP;
Organism Homo sapiens (Human)

PRO ID PR:Q2M3C7
DAG View
PRO Name A-kinase anchor protein SPHKAP (human)
Definition An A-kinase anchor protein SPHKAP that is encoded in the genome of human.
Short Label hSPHKAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2M3C7 (SPHKAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
Y272 Phosphorylation PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
T809 Phosphorylation PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus
S857 Phosphorylation PhosphoSitePlus
T864 Phosphorylation PhosphoSitePlus
T971 Phosphorylation PhosphoSitePlus
S1071 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
T1191 Phosphorylation PhosphoSitePlus
S1209 Phosphorylation PhosphoSitePlus
S1211 Phosphorylation PhosphoSitePlus
S1212 Phosphorylation PhosphoSitePlus
S1216 Phosphorylation PhosphoSitePlus
T1220 Phosphorylation PhosphoSitePlus
S1225 Phosphorylation PhosphoSitePlus
S1259 Phosphorylation PhosphoSitePlus
S1340 Phosphorylation PhosphoSitePlus
S1367 Phosphorylation PhosphoSitePlus
K1380 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 T32 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S35 R35 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y272 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T809 M809 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S857 F857 Biomuta DOID:4159 / skin cancer [ cosmic ]
T864 M864 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:3277 / thymus cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1071 R1071 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1124 G1124 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1209 I1209 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1211 F1211 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1216 N1216 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
S1225 Y1225 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1259 Y1259 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1259 F1259 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1340 F1340 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1367 Y1367 Biomuta DOID:363 / uterine cancer [ icgc ]