iPTMnet Report for Q2M2Z5 (KIZ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2M2Z5 / KIZ_HUMAN
Protein Name Centrosomal protein kizuna
Gene Name Name: KIZ
Synonyms:C20orf19,NCRNA00153,PLK1S1;ORFNames:HT013;
Organism Homo sapiens (Human)

PRO ID PR:Q2M2Z5
DAG View
PRO Name centrosomal protein kizuna (human)
Definition A centrosomal protein kizuna that is encoded in the genome of human.
Short Label hKIZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2M2Z5 (KIZ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
C50 Methylation IEDB 31844290
K64 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S229 Phosphorylation IEDB 35494241
S263 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S317 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S321 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
T379 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25558830, 16980960
T379 Phosphorylation P53350 (PLK1) neXtProt   PhosphoSitePlus   Signor 16980960
S435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
T605 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S647 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S650 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S652 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T665 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S317 Phosphorylation HPRD 18669648, 17081983
S321 Phosphorylation HPRD 18669648, 17081983
S647 Phosphorylation HPRD 18669648
S650 Phosphorylation HPRD 18669648
S652 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C50 Y50 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S283 C283 Biomuta DOID:263 / kidney cancer [ cosmic ]
S435 R435 Biomuta DOID:1319 / brain cancer [ cosmic ]
S435 C435 Biomuta DOID:1324 / lung cancer [ cosmic ]