iPTMnet Report for Q2KHR3 (QSER1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q2KHR3 / QSER1_HUMAN
Protein Name Glutamine and serine-rich protein 1
Gene Name Name: QSER1
Organism Homo sapiens (Human)

PRO ID PR:Q2KHR3
DAG View
PRO Name glutamine and serine-rich protein 1 (human)
Definition A glutamine and serine-rich protein 1 that is encoded in the genome of human.
Short Label hQSER1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q2KHR3 (QSER1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S5 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T11 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S17 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
R26 Methylation PhosphoSitePlus
T74 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T104 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S105 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T108 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T111 O-Glycosylation GlyGen 21158410, 32574038
S131 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S187 Phosphorylation PhosphoSitePlus
S234 O-Glycosylation GlyGen 21606357
S236 Phosphorylation PhosphoSitePlus
T242 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T242 Phosphorylation PhosphoSitePlus
S245 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
K281 Methylation PhosphoSitePlus
K281 Sumoylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
S282 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S282 Phosphorylation PhosphoSitePlus
S284 O-Glycosylation GlyGen 32574038
S299 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T306 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S308 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S310 O-Glycosylation GlyGen 25813380
K368 Ubiquitination PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
T490 Phosphorylation PhosphoSitePlus
Y493 Phosphorylation PhosphoSitePlus
T504 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S512 Phosphorylation PhosphoSitePlus
S521 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
K549 Sumoylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S586 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S586 Phosphorylation PhosphoSitePlus   UniProt 23186163
S595 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T596 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
K598 Ubiquitination PhosphoSitePlus
S600 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
Y606 Phosphorylation HPRD   PhosphoSitePlus 17924679
S607 Phosphorylation PhosphoSitePlus
S613 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231, ...17924679
S615 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S634 Phosphorylation PhosphoSitePlus
S660 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T666 Phosphorylation PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
K677 Sumoylation PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
K803 Acetylation PhosphoSitePlus
K803 Sumoylation PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
T865 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus   UniProt 23186163
K887 Sumoylation PhosphoSitePlus
S931 Phosphorylation HPRD   PhosphoSitePlus 19413330, 20068231
T949 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T959 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 32938750, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
S966 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
K978 Acetylation PhosphoSitePlus
T983 Phosphorylation HPRD   phospho.ELM 18669648
S987 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1010 Phosphorylation PhosphoSitePlus
S1011 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus
S1032 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1058 Sumoylation PhosphoSitePlus
K1083 Sumoylation PhosphoSitePlus
Y1113 Phosphorylation PhosphoSitePlus
T1114 Phosphorylation PhosphoSitePlus
K1141 Sumoylation PhosphoSitePlus
K1162 Ubiquitination PhosphoSitePlus
R1171 Methylation PhosphoSitePlus
R1178 Methylation PhosphoSitePlus
R1185 Methylation PhosphoSitePlus
T1199 Phosphorylation PhosphoSitePlus
T1207 Phosphorylation HPRD   phospho.ELM 18669648
S1211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 19664994, ...19651622, 18669648, 20068231
S1227 Phosphorylation HPRD   phospho.ELM 19651622, 18669648
S1228 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 17525332, 18669648, ...20068231
S1230 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18452278, ...19651622, 18669648, 20068231
S1231 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17525332, 21406692, ...18452278, 19651622, 18669648
S1239 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
T1248 Phosphorylation PhosphoSitePlus
T1256 Phosphorylation PhosphoSitePlus
S1257 Phosphorylation PhosphoSitePlus
T1270 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1271 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 32938750, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1271 Phosphorylation PhosphoSitePlus
S1272 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1274 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1277 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1277 Phosphorylation PhosphoSitePlus
T1278 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
T1283 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 22661428, 29237092, 34725712, 32119511, 21158410, 28411811, 32574038, 35132862, 28604694, 20305658, 28657654, 34846842, 33214551, 30379171, 32522876, 30059200, 21740066, 35254053, 34019948, 20068230
K1292 Sumoylation PhosphoSitePlus
K1316 Sumoylation PhosphoSitePlus
T1341 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18452278, ...19651622, 18669648, 19415658, 19690332, 20068231
T1346 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648, 20068231, ...19651622
S1348 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18452278, ...19651622, 18669648, 19415658
Y1354 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K1388 Sumoylation PhosphoSitePlus
K1388 Ubiquitination PhosphoSitePlus
K1393 Ubiquitination PhosphoSitePlus
Y1411 Phosphorylation PhosphoSitePlus
K1493 Sumoylation PhosphoSitePlus
K1550 Methylation PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus
Y1552 Phosphorylation PhosphoSitePlus
S1558 Phosphorylation PhosphoSitePlus
K1583 Ubiquitination PhosphoSitePlus
S1626 Phosphorylation PhosphoSitePlus
T1629 Phosphorylation PhosphoSitePlus
K1633 Sumoylation PhosphoSitePlus
K1654 Ubiquitination PhosphoSitePlus
K1714 Ubiquitination PhosphoSitePlus
K1733 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S105 F105 Biomuta DOID:4159 / skin cancer [ cosmic ]
S234 F234 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S488 T488 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S512 F512 Biomuta DOID:4159 / skin cancer [ cosmic ]
S521 P521 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S552 L552 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S580 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S586 F586 Biomuta [ cosmic ]
S613 R613 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S634 G634 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K685 T685 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K824 N824 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K824 T824 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S832 L832 Biomuta DOID:1319 / brain cancer [ icgc ]
S842 G842 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T865 I865 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K887 E887 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K887 N887 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S931 L931 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S987 P987 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1011 G1011 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1013 N1013 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1032 C1032 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1178 W1178 Biomuta DOID:363 / uterine cancer [ icgc ]
R1185 H1185 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1185 C1185 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1227 C1227 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1248 A1248 Biomuta DOID:1612 / breast cancer [ icgc ]
S1257 Y1257 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1316 M1316 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K1493 E1493 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1626 R1626 Biomuta DOID:4159 / skin cancer [ cosmic ]