iPTMnet Report for Q27J81 (INF2)
Protein Information
UniProt AC / UniProt ID | Q27J81 / INF2_HUMAN |
Protein Name | Inverted formin-2 |
Gene Name | Name: INF2 Synonyms:C14orf151,C14orf173; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q27J81 |
PRO Name | inverted formin-2 (human) |
Definition | An inverted formin-2 that is encoded in the genome of human. |
Short Label | hINF2 |
Category | organism-gene |
Q27J81 (INF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
K4 | Methylation | score1 | PhosphoSitePlus | |||
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
T26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
T100 | Phosphorylation | score1 | PhosphoSitePlus | |||
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
T134 | Phosphorylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
S351 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K355 | Ubiquitination | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
S371 | O-Glycosylation | score1 | GlyGen | 23301498, 34725712, 33465208, ... | ||
S371 | Phosphorylation | score1 | PhosphoSitePlus | |||
S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
T376 | Phosphorylation | score1 | PhosphoSitePlus | |||
T378 | Phosphorylation | score1 | PhosphoSitePlus | |||
T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S527 | Phosphorylation | score1 | PhosphoSitePlus | |||
T561 | Phosphorylation | score1 | PhosphoSitePlus | |||
K565 | Ubiquitination | score1 | PhosphoSitePlus | |||
K566 | Ubiquitination | score1 | PhosphoSitePlus | |||
K571 | Ubiquitination | score1 | PhosphoSitePlus | |||
S574 | Phosphorylation | score1 | PhosphoSitePlus | 21851590 | ||
S574 | Phosphorylation | O14757 (CHEK1) | score1 | PhosphoSitePlus | 21851590 | |
S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
S607 | Phosphorylation | score1 | PhosphoSitePlus | |||
K612 | Ubiquitination | score1 | PhosphoSitePlus | |||
K614 | Ubiquitination | score1 | PhosphoSitePlus | |||
T617 | Phosphorylation | score1 | PhosphoSitePlus | |||
K636 | Ubiquitination | score1 | PhosphoSitePlus | |||
K666 | Acetylation | score1 | PhosphoSitePlus | |||
K666 | Ubiquitination | score1 | PhosphoSitePlus | |||
K673 | Ubiquitination | score1 | PhosphoSitePlus | |||
K682 | Ubiquitination | score1 | PhosphoSitePlus | |||
K792 | Ubiquitination | score1 | PhosphoSitePlus | |||
K810 | Ubiquitination | score1 | PhosphoSitePlus | |||
S811 | Phosphorylation | score1 | PhosphoSitePlus | |||
K846 | Ubiquitination | score1 | PhosphoSitePlus | |||
T850 | Phosphorylation | score1 | PhosphoSitePlus | |||
K853 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y865 | Phosphorylation | score1 | PhosphoSitePlus | |||
T866 | Phosphorylation | score1 | PhosphoSitePlus | |||
K889 | Ubiquitination | score1 | PhosphoSitePlus | |||
K962 | Acetylation | score1 | PhosphoSitePlus | |||
K966 | Acetylation | score1 | PhosphoSitePlus | |||
K966 | Ubiquitination | score1 | PhosphoSitePlus | |||
R993 | Methylation | score1 | PhosphoSitePlus | |||
S1000 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1026 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
T1054 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1076 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1077 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1079 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1083 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1115 | Methylation | score1 | PhosphoSitePlus | |||
S1126 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1132 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1136 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1147 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
T1148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1149 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
S1158 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1179 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231, 24275569, 18318008 | ||
S1183 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1187 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1192 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163 | ||
S1194 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T1199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1201 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1204 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1206 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
S1227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1229 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 17081983 | ||
S1237 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1242 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T134 | Phosphorylation | score0 | HPRD | 20068231 | ||
S135 | Phosphorylation | score0 | HPRD | 20068231 | ||
T420 | Phosphorylation | score0 | HPRD | 20068231 | ||
S586 | Phosphorylation | score0 | HPRD | 20068231 | ||
S588 | Phosphorylation | score0 | HPRD | 18669648 | ||
S589 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T850 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1147 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
T1148 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S1149 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983 | ||
S1158 | Phosphorylation | score0 | HPRD | 18669648 | ||
T1179 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 17081983, ... | ||
S1183 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
T1187 | Phosphorylation | score0 | HPRD | 18510355, 19651622 | ||
S1188 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 18452278 | ||
S1192 | Phosphorylation | score0 | HPRD | 19651622, 19691289, 20068231 | ||
S1194 | Phosphorylation | score0 | HPRD | 17081983 | ||
T1199 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1201 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1202 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1204 | Phosphorylation | score0 | HPRD | 18452278, 19691289, 17081983 | ||
T1206 | Phosphorylation | score0 | HPRD | 17081983, 18452278 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T134 | Phosphorylation | score0 | HPRD | 20068231 | ||
S135 | Phosphorylation | score0 | HPRD | 20068231 | ||
T420 | Phosphorylation | score0 | HPRD | 20068231 | ||
S586 | Phosphorylation | score0 | HPRD | 20068231 | ||
S588 | Phosphorylation | score0 | HPRD | 18669648 | ||
S589 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T850 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1147 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
T1148 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
S1149 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983 | ||
S1158 | Phosphorylation | score0 | HPRD | 18669648 | ||
T1179 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 17081983, ... | ||
S1183 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
T1187 | Phosphorylation | score0 | HPRD | 18510355, 19651622 | ||
S1188 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 18452278 | ||
S1192 | Phosphorylation | score0 | HPRD | 19651622, 19691289, 20068231 | ||
S1194 | Phosphorylation | score0 | HPRD | 17081983 | ||
T1199 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1201 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1202 | Phosphorylation | score0 | HPRD | 17081983 | ||
S1204 | Phosphorylation | score0 | HPRD | 18452278, 19691289, 17081983 | ||
T1206 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S1229 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S23 | L23 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T561 | P561 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S574 | F574 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S607 | F607 | Biomuta | DOID:4159 / skin cancer [ icgc ] | |
K966 | N966 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
R993 | C993 | Biomuta | DOID:184 / bone cancer [ cosmic ] [ cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ] | |
S1136 | Y1136 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1136 | F1136 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S1147 | N1147 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
T1179 | M1179 | Biomuta | [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:1115 / sarcoma [ icgc ] | |
T1179 | R1179 | Biomuta | [ cosmic ] | |
S1237 | F1237 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |