Protein Information

Cytoscape View


UniProt AC / UniProt ID Q1L5Z9 / LONF2_HUMAN
Protein Name LON peptidase N-terminal domain and RING finger protein 2
Gene Name Name: LONRF2
Synonyms:RNF192;
Organism Homo sapiens (Human)

PRO ID PR:Q1L5Z9
DAG View
PRO Name LON peptidase N-terminal domain and RING finger protein 2 (human)
Definition A LON peptidase N-terminal domain and RING finger protein 2 that is encoded in the genome of human.
Short Label hLONRF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q1L5Z9 (LONRF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K152 Acetylation PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y290 D290 Biomuta DOID:363 / uterine cancer [ icgc ]
S300 Y300 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ]
T601 M601 Biomuta DOID:2531 / hematologic cancer [ cosmic ]