iPTMnet Report for Q16836 (HADH)
Protein Information
UniProt AC / UniProt ID | Q16836 / HCDH_HUMAN |
Protein Name | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor |
Gene Name | Name: HADH Synonyms:HAD; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16836 |
PRO Name | hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (human) |
Definition | A hydroxyacyl-coenzyme A dehydrogenase, mitochondrial that is encoded in the genome of human. |
Short Label | hHADH |
Category | organism-gene |
Q16836 (HADH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
R75 | Methylation | score1 | PhosphoSitePlus | |||
K76 | Acetylation | score1 | PhosphoSitePlus | |||
K80 | Acetylation | score1 | PhosphoSitePlus | |||
K81 | Acetylation | score1 | PhosphoSitePlus | |||
K87 | Acetylation | score1 | PhosphoSitePlus | |||
K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
K132 | Acetylation | score1 | PhosphoSitePlus | |||
K136 | Acetylation | score1 | PhosphoSitePlus | |||
K179 | Acetylation | score1 | PhosphoSitePlus | |||
K185 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
K202 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K212 | Acetylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
T214 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y234 | Phosphorylation | score1 | PhosphoSitePlus | |||
K241 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
K249 | Acetylation | score1 | PhosphoSitePlus | |||
Y264 | Phosphorylation | score1 | PhosphoSitePlus | |||
T269 | Phosphorylation | score1 | PhosphoSitePlus | |||
T270 | Phosphorylation | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K304 | Acetylation | score1 | PhosphoSitePlus | |||
K312 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K312 | Methylation | score1 | PhosphoSitePlus | |||
K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y313 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K127 | E127 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K132 | E132 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K136 | N136 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K202 | E202 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
Y226 | H226 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |