iPTMnet Report for Q16526 (CRY1)
Protein Information
UniProt AC / UniProt ID | Q16526 / CRY1_HUMAN |
Protein Name | Cryptochrome-1 |
Gene Name | Name: CRY1 Synonyms:PHLL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16526 |
PRO Name | cryptochrome-1 (human) |
Definition | A cryptochrome-1 that is encoded in the genome of human. |
Short Label | hCRY1 |
Category | organism-gene |
Q16526 (CRY1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Phosphorylation | score1 | PRO | ||||
Ubiquitination | score1 | PRO | ||||
S71 | Phosphorylation | Q13131 (PRKAA1) | score4 | neXtProt RLIMS-P Signor | 21892142, 30500822, 19833968 | |
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K151 | Acetylation | score1 | PhosphoSitePlus | |||
K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
S247 | Phosphorylation | P28482 (MAPK1) | score2 | neXtProt | 15298678 | |
C259 | Methylation | score1 | IEDB | 31844290 | ||
S280 | Phosphorylation | score4 | neXtProt RLIMS-P | 30500822, 19833968 | ||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y432 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y494 | Phosphorylation | score0 | HPRD | 18083107 | ||
S568 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000047073 (hCRY1/PhosSer+) | p | PRO | |||
PR:000047074 (hCRY1/pSerUbiq+) | p | PRO | |||
PR:000047074 (hCRY1/pSerUbiq+) | ub | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K89 | E89 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K228 | N228 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
S492 | L492 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S568 | N568 | Biomuta | DOID:363 / uterine cancer [ icgc ] |