iPTMnet Report for Q16270 (IGFBP7)
Protein Information
UniProt AC / UniProt ID | Q16270 / IBP7_HUMAN |
Protein Name | Insulin-like growth factor-binding protein 7 precursor |
Gene Name | Name: IGFBP7 Synonyms:MAC25,PSF; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16270 |
PRO Name | insulin-like growth factor-binding protein 7 (human) |
Definition | An insulin-like growth factor-binding protein 7 that is encoded in the genome of human. |
Short Label | hIGFBP7 |
Category | organism-gene |
Q16270 (IGFBP7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T31 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S39 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
S142 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
N171 | N-Glycosylation | score3 | GlyGen UniProt | 8939990 | ||
T188 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
Y201 | Phosphorylation | score1 | PhosphoSitePlus | |||
T206 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T220 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
T230 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S236 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S239 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 26091039 | ||
S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
T264 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K146 | T146 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |