iPTMnet Report for Q16143 (SNCB)
Protein Information
| UniProt AC / UniProt ID | Q16143 / SYUB_HUMAN |
| Protein Name | Beta-synuclein |
| Gene Name | Name: SNCB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16143 |
| PRO Name | beta-synuclein (human) |
| Definition | A beta-synuclein that is encoded in the genome of human. |
| Short Label | hSNCB |
| Category | organism-gene |
DAG ViewQ16143 (SNCB) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K6 | Acetylation | score1 | PhosphoSitePlus | |||
| K12 | Acetylation | score1 | PhosphoSitePlus | |||
| K21 | Acetylation | score1 | PhosphoSitePlus | |||
| T27 | O-Glycosylation | score1 | GlyGen | 28657654 | ||
| Y39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S54 | O-Glycosylation | score1 | GlyGen | 28657654 | ||
| T59 | O-Glycosylation | score1 | GlyGen | 28657654 | ||
| S118 | Phosphorylation | Q9H4B4 (PLK3) , P53350 (PLK1) , Q9NYY3 (PLK2) , P34947 (GRK5) | score4 | HPRD neXtProt PhosphoSitePlus Signor UniProt | 10852916, 19889641 | |
| Y127 | Phosphorylation | O14757 (CHEK1) | score3 | PhosphoSitePlus Signor | 21699177 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K12 | T12 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K21 | N21 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y39 | C39 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| T59 | N59 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
