iPTMnet Report for Q15819 (UBE2V2)
Protein Information
UniProt AC / UniProt ID | Q15819 / UB2V2_HUMAN |
Protein Name | Ubiquitin-conjugating enzyme E2 variant 2 |
Gene Name | Name: UBE2V2 Synonyms:MMS2,UEV2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15819 |
PRO Name | ubiquitin-conjugating enzyme E2 variant 2 (human) |
Definition | A ubiquitin-conjugating enzyme E2 variant 2 that is encoded in the genome of human. |
Short Label | hUBE2V2 |
Category | organism-gene |
Q15819 (UBE2V2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
R61 | Methylation | score1 | PhosphoSitePlus | |||
K66 | Acetylation | score1 | PhosphoSitePlus | |||
K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Acetylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
R101 | Methylation | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
R123 | Methylation | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
K133 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | F4 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S4 | Y4 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T5 | I5 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] |