iPTMnet Report for Q15758 (SLC1A5)
Protein Information
UniProt AC / UniProt ID | Q15758 / AAAT_HUMAN |
Protein Name | Neutral amino acid transporter B(0) |
Gene Name | Name: SLC1A5 Synonyms:ASCT2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15758 |
PRO Name | neutral amino acid transporter B(0) (human) |
Definition | A neutral amino acid transporter B(0) that is encoded in the genome of human. |
Short Label | hSLC1A5 |
Category | organism-gene |
Q15758 (SLC1A5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
N163 | N-Glycosylation | score2 | GlyGen | 25862406 | ||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
N212 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 29741879, 24190977, ... | ||
K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
K372 | Ubiquitination | score1 | PhosphoSitePlus | |||
C467 | Methylation | score1 | IEDB | 31844290 | ||
S493 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163 | ||
T494 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
S503 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
K522 | Sumoylation | score1 | PhosphoSitePlus | |||
K522 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y524 | Phosphorylation | score1 | PhosphoSitePlus | |||
R525 | Methylation | score1 | PhosphoSitePlus | |||
T532 | Phosphorylation | score1 | PhosphoSitePlus | |||
S535 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 18669648, ... | ||
K537 | Acetylation | score1 | PhosphoSitePlus | |||
K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
S539 | Phosphorylation | score2 | IEDB PhosphoSitePlus UniProt | 34433824, 23186163 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score0 | HPRD | 18578522 | ||
S198 | Phosphorylation | score0 | HPRD | 20068231 | ||
S493 | Phosphorylation | score0 | HPRD | 19651622, 18578522, 20068231 | ||
T494 | Phosphorylation | score0 | HPRD | 18578522, 18669648, 20068231 | ||
S503 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y524 | Phosphorylation | score0 | HPRD | 19901323, 18578522 | ||
T532 | Phosphorylation | score0 | HPRD | 19413330, 18578522 | ||
S535 | Phosphorylation | score0 | HPRD | 19651622, 18578522, 18669648, ... | ||
S539 | Phosphorylation | score0 | HPRD | 18578522 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S198 | L198 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
C467 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S493 | I493 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K522 | R522 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
R525 | Q525 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T532 | M532 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
S535 | F535 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K537 | E537 | Biomuta | DOID:363 / uterine cancer [ icgc ] |