iPTMnet Report for Q15699 (ALX1)
Protein Information
UniProt AC / UniProt ID | Q15699 / ALX1_HUMAN |
Protein Name | ALX homeobox protein 1 |
Gene Name | Name: ALX1 Synonyms:CART1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15699 |
PRO Name | ALX homeobox protein 1 (human) |
Definition | An ALX homeobox protein 1 that is encoded in the genome of human. |
Short Label | hALX1 |
Category | organism-gene |
Q15699 (ALX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S12 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 23186163 | ||
S45 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K48 | Sumoylation | score1 | PhosphoSitePlus | |||
S69 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
S128 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
T169 | Phosphorylation | score1 | PhosphoSitePlus | |||
T172 | Phosphorylation | score1 | PhosphoSitePlus | |||
S306 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
R312 | Methylation | score1 | PhosphoSitePlus | |||
S323 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S128 | F128 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S128 | C128 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
R312 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] | |
R312 | Q312 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
S323 | L323 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |