iPTMnet Report for Q15555 (MAPRE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15555 / MARE2_HUMAN
Protein Name Microtubule-associated protein RP/EB family member 2
Gene Name Name: MAPRE2
Synonyms:RP1;
Organism Homo sapiens (Human)

PRO ID PR:Q15555
DAG View
PRO Name microtubule-associated protein RP/EB family member 2 (human)
Definition A microtubule-associated protein RP/EB family member 2 that is encoded in the genome of human.
Short Label hMAPRE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15555 (MAPRE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
P2 Acetylation UniProt 22814378
S9 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27030108, 23186163
T33 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
S72 Phosphorylation IEDB 30784271
K105 Acetylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
K165 Sumoylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
Y167 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455
K193 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
S200 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087, 17081983
K207 Ubiquitination PhosphoSitePlus
S208 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S209 Phosphorylation PhosphoSitePlus   RLIMS-P 27030108
K213 Ubiquitination PhosphoSitePlus
S216 O-Glycosylation GlyGen 28411811, 28510447, 29351928
S216 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T217 Phosphorylation PhosphoSitePlus   RLIMS-P 27030108
S219 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
S222 Phosphorylation PhosphoSitePlus
S223 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 18669648, 27030108, 17287340
K225 Acetylation PhosphoSitePlus
S228 Phosphorylation phospho.ELM 18669648
S232 Phosphorylation phospho.ELM 18669648
S234 Phosphorylation phospho.ELM 18669648
K235 Ubiquitination PhosphoSitePlus
S236 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 23844040
K238 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 19413330, 20068231
Y167 Phosphorylation HPRD 15592455
S200 Phosphorylation HPRD 19651622, 18088087, 17081983
T202 Phosphorylation HPRD 19651622
S208 Phosphorylation HPRD 18669648
S216 Phosphorylation HPRD 18669648, 20068231
S219 Phosphorylation HPRD 18669648, 17287340
S223 Phosphorylation HPRD 18669648, 17287340
S228 Phosphorylation HPRD 18669648
S232 Phosphorylation HPRD 18669648
S234 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
P2 L2 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
P2 H2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S9 F9 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y49 F49 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S72 Y72 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
K126 E126 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K155 N155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y167 H167 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y167 C167 Biomuta DOID:363 / uterine cancer [ icgc ]
T202 A202 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K213 T213 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K213 N213 Biomuta DOID:9256 / colorectal cancer [ cosmic ]