iPTMnet Report for Q15386 (UBE3C)
Protein Information
UniProt AC / UniProt ID | Q15386 / UBE3C_HUMAN |
Protein Name | Ubiquitin-protein ligase E3C |
Gene Name | Name: UBE3C Synonyms:KIAA0010; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15386 |
PRO Name | ubiquitin-protein ligase E3C (human) |
Definition | A ubiquitin-protein ligase E3C that is encoded in the genome of human. |
Short Label | hUBE3C |
Category | organism-gene |
Q15386 (UBE3C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
S54 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447 | ||
Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y66 | Phosphorylation | score1 | PhosphoSitePlus | |||
C76 | Methylation | score1 | IEDB | 31844290 | ||
K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y225 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
S366 | Phosphorylation | score1 | PhosphoSitePlus | |||
S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
C429 | Methylation | score1 | IEDB | 31844290 | ||
Y447 | Phosphorylation | score1 | PhosphoSitePlus | |||
S464 | Phosphorylation | score1 | PhosphoSitePlus | |||
S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
K558 | Ubiquitination | score1 | PhosphoSitePlus | |||
K565 | Ubiquitination | score1 | PhosphoSitePlus | |||
K610 | Ubiquitination | score1 | PhosphoSitePlus | |||
K635 | Ubiquitination | score1 | PhosphoSitePlus | |||
K638 | Ubiquitination | score1 | PhosphoSitePlus | |||
S672 | Phosphorylation | score1 | PhosphoSitePlus | |||
K700 | Ubiquitination | score1 | PhosphoSitePlus | |||
K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
K739 | Ubiquitination | score1 | PhosphoSitePlus | |||
S741 | Phosphorylation | score0 | RLIMS-P | 35914132 | ||
K749 | Ubiquitination | score1 | PhosphoSitePlus | |||
K782 | Ubiquitination | score1 | PhosphoSitePlus | |||
K793 | Ubiquitination | score1 | PhosphoSitePlus | |||
S845 | Phosphorylation | score1 | PhosphoSitePlus | |||
T850 | Phosphorylation | score1 | PhosphoSitePlus | |||
S851 | Phosphorylation | score1 | PhosphoSitePlus | |||
K868 | Ubiquitination | score1 | PhosphoSitePlus | |||
K903 | Ubiquitination | Q15386 (UBE3C) | score2 | UniProt | 32039437 | |
K907 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1004 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1008 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1013 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1056 | Ubiquitination | score1 | PhosphoSitePlus |
Q15386 (UBE3C) as PTM Enzyme
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K25 | N25 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K25 | E25 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K25 | R25 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K235 | N235 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K793 | N793 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K868 | N868 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc, tcga ] | |
K903 | N903 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |