iPTMnet Report Q15369 ELOC

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q15369 / ELOC_HUMAN
Protein Name	Elongin-C
Gene Name	Name: ELOC Synonyms:TCEB1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q15369 DAG View
PRO Name	elongin-C (human)
Definition	An elongin-C that is encoded in the genome of human.
Short Label	hELOC
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q15369 (ELOC) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K6	Ubiquitination		score1	PhosphoSitePlus
	C11	S-Nitrosylation		score0	dbSNO	19483679, 2212679, 22126794, ...26338901
	Y18	Phosphorylation		score1	PhosphoSitePlus
	K20	Ubiquitination		score1	PhosphoSitePlus
	S24	Phosphorylation		score1	PhosphoSitePlus
	K32	Acetylation		score1	PhosphoSitePlus
	K32	Sumoylation		score1	PhosphoSitePlus
	K32	Ubiquitination		score1	PhosphoSitePlus
	T38	Phosphorylation		score1	PhosphoSitePlus
	K43	Ubiquitination		score1	PhosphoSitePlus
	S47	Phosphorylation		score1	PhosphoSitePlus
	K72	Acetylation		score1	PhosphoSitePlus
	K72	Ubiquitination		score1	PhosphoSitePlus
	C74	Methylation		score1	IEDB	31844290

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S71	Phosphorylation		score0	HPRD	20068231

Q15369 (ELOC) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	Q02539 (H1-1)	S183	score1	Signor	20551309

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S24	C24	Biomuta		DOID:2394 / ovarian cancer [ cosmic, icgc ]
T38	S38	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
S71	L71	Biomuta		DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]