iPTMnet Report for Q15361 (TTF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15361 / TTF1_HUMAN
Protein Name Transcription termination factor 1
Gene Name Name: TTF1
Organism Homo sapiens (Human)

PRO ID PR:Q15361
DAG View
PRO Name transcription termination factor 1 (human)
Definition A transcription termination factor 1 that is encoded in the genome of human.
Short Label hTTF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15361 (TTF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation HPRD   PhosphoSitePlus 20068231
S15 Phosphorylation HPRD   PhosphoSitePlus 20068231
S41 Phosphorylation HPRD   PhosphoSitePlus 19007248, 19691289
S47 Phosphorylation HPRD 19007248, 20068231
S64 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
S65 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19651622, ...18669648, 20068231
S81 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S240 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
T248 Phosphorylation PhosphoSitePlus   UniProt 23186163
S253 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
K398 Acetylation PhosphoSitePlus
S403 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19691289, ...20068231
K434 Ubiquitination PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
Y476 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19690332, 18452278
S478 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 18452278
S481 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18452278, ...18669648, 19690332, 20068231
S487 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...19691289, 18452278, 18669648, 24275569, 19690332, 20068231
K506 Ubiquitination PhosphoSitePlus
K514 Ubiquitination PhosphoSitePlus
K528 Methylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
K542 Ubiquitination PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
K688 Acetylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus
K695 Ubiquitination PhosphoSitePlus
K700 Acetylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
K738 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K747 Ubiquitination PhosphoSitePlus
K765 Ubiquitination PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K857 Acetylation PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
Y868 Phosphorylation PhosphoSitePlus
S872 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...19691289, 18452278, 19651622, 18669648, 24275569, 16565220, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S240 W240 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y357 C357 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S472 F472 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S650 N650 Biomuta DOID:4159 / skin cancer [ cosmic ]
K688 N688 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S710 L710 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K747 N747 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]