iPTMnet Report for Q15269 (PWP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15269 / PWP2_HUMAN
Protein Name Periodic tryptophan protein 2 homolog
Gene Name Name: PWP2
Synonyms:PWP2H;
Organism Homo sapiens (Human)

PRO ID PR:Q15269
DAG View
PRO Name periodic tryptophan protein 2 homolog (human)
Definition A periodic tryptophan protein 2 that is encoded in the genome of human.
Short Label hPWP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15269 (PWP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
K43 Methylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S47 Phosphorylation HPRD 20068231
T54 O-Glycosylation GlyGen 30379171, 33214551, 34725712, ...32119511
T54 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
R253 Methylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K279 Acetylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
T543 O-Glycosylation GlyGen 30379171, 33214551, 34725712, ...32119511
K600 Ubiquitination PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
Y632 Phosphorylation HPRD   PhosphoSitePlus 20068231
K662 Ubiquitination PhosphoSitePlus
K691 Methylation PhosphoSitePlus
K700 Acetylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
S744 Phosphorylation HPRD 20068231
T746 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
K773 Ubiquitination PhosphoSitePlus
T791 Phosphorylation HPRD 20068231
S792 Phosphorylation HPRD 20068231
S860 Phosphorylation PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus
S891 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19007248, 20068231, ...18452278
S898 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231, 18452278
S902 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S913 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19007248, 20068231, ...18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K662 Q662 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S707 L707 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T791 I791 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S860 L860 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]